The Trust

Pharmacy Aseptic Unit

The Aseptic Unit in the Pharmacy Department supports the Macmillan Cancer Resource Centre by manufacturing chemotherapy injections in a sterile environment.


A sterile environment is created though a number of different measures:

  • Design of the unit (eg the air is filtered to reduce airborne contaminants)
  • Regular cleaning
  • Special clothing (the operators wear special hats, gloves, tunics and shoes)
  • Decontamination of products (alcohol spray is used to clean all the components for the injections)
  • Isolators (injections are manufactured in a sealed unit to protect the operator from the chemotherapy and to prevent contamination of the product)

Strict procedures are also followed to ensure accuracy. Checks are carried out at every stage of the manufacturing process:

  • The prescription, worksheet, labels, active drug and diluent are checked by a pharmacist.
  • A second technician is present whilst the drug is being dispensed in the isolator to check the volumes drawn up.
  • A final check of the product is carried out by a pharmacist before it can be released for use on the ward.

All regional Hospital Aseptic Units are monitored regularly by Quality Control North West to ensure that high standards are maintained.

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