Oncology Research Team

Who are we?

We are a small team specialising in cancer research at Macclesfield District General Hospital. We consist of five oncology research sisters, responsible for running clinical trials and three clinical trials administrators, providing general administrative support and trial data collection.

What do we do?

The job of the Oncology Research Team is to set up and run cancer clinical trials at Macclesfield District General Hospital so that patients do not have to travel to Christie Hospital to be offered the chance to take part in research. Cancer clinical trials are carried out on large groups of patients to try to find new and better treatments for cancer. They are the only reliable way to find out if a new treatment is better than what is already available.

What trials do we have running?

The following is a list of the trials we are currently recruiting to at Macclesfield District General Hospital. Clicking on the name of a trial will link you to the Cancer Research UK website search facility for clinical trials.

• ARTEMIS – Avastin Randomised Trial with neo-adjuvant chemotherapy for patients with   early HER 2 negative breast cancer.
• BOXIT– Bladder Cox 2 Inhibition trial.
• CREW– A study to explore recovery of health and well being following colo-rectal cancer.
• ET– Platinum based chemotherapy v non-platinum chemotherapy in patients with non-small cell lung cancer.  
• FOXTROT – Assessing whether pre-operative chemotherapy and/or a monoclonal       antibody improve outcome in colon cancer.    
• FRAGMATIC – The effect of FRAGMin added to standard therapy in patients with lung cancer.
• IBIS II PREVENTION– International Breast Cancer Intervention Study of anastrozole vs. placebo in postmenopausal women at increased risk of breast cancer.
• IBIS II DCIS- International Breast Cancer Intervention Study of tamoxifen vs. anastrazole in postmenopausal women with Ductal Carcinoma In-Situ (DCIS).
• ICICLE  - Investigation of the genetics of insitu carcinoma of the ductal subtype.
• MALCS–UK national mesothelioma and lung cancer study.
• MELANOMA LIFESTYLE – Patients with a primary melanoma.
• MODAFINIL– Treatment of fatigue in lung cancer.
• NSCCG– National study of colorectal genetics.
• NSHLG – National Study of Hodgkin’s Lymphoma.
• PATCH  - A trial of transcutaneous oestrogen patches versus LHRH analogues in prostate cancer.
• PERSEPHONE– Duration of Trastuzumab or Herceptin with Chemotherapy in Women with Early Breast Cancer six months versus twelve.
• POETIC­– A trial of Peri-operative Endocrince Therapy.
• SCOT – A study of adjuvant chemotherapy in colorectal cancer.
• SOCS – Identification of the genetics and environmental determinants of oesophageal and gastric adenocarcinomas.
• SPIRIT2– Comparison of imatinib vs dasatinib in patients with chronic myeloid leukaemia.
• SUPREMO - an MRC phase III randomised trial to assess the role of adjuvant chest wall irradiation in intermediate risk, operable breast cancer following mastectomy.
• TELESTO – Trial of Deferasirox in patients with myelodysplastic syndrome and transfusional iron overload.
• TNT– Triple Negative breast cancer trial.
• UKFPCS – UK Genetic Prostate Cancer study.
• ZICE – Zoledronate vs Ibandronate comparative evaluation in treatment of breast cancer.
• 70 + - Management of breast cancer for woman aged 70 +

More information

We are available Monday to Friday from 8.30am - 5.00pm, except bank holidays on 01625 663115. The nature of our job means we are often in and out of the office. Please leave a message on our answer phone or for urgent calls, ring the hospital switchboard on 01625 421000 and ask them to bleep 5078.